Gene expression data obtained by DNA microarrays are represented in the basis of the Probe IDs. On the other hand, for most species whose genome sequencing were completed the genes registered in the KaPPA-View4 are identified by gene IDs which are provided by genome annotation teams. Therefore it is necessary for you to consider the correspondence between Probe IDs and Gene IDs when you analyze your microarray data on KaPPA-View4. Particularly, in such cases that a probe could hybridize to several gene transcripts and/or a gene is detectable by several probes, researchers sometimes face difficult situation to determine which probe is the most representative for the gene and how to compile the data.
KaPPA-Average organizes such a multiple to multiple relationships between probe IDs and gene IDs, and processes probe ID-based gene expression data to convert to gene ID-based data. When a gene is detectable by several probes, the expression value of the gene is calculated as the average of the probe values.
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